Anti-LBP antibody (221-270 aa) (STJ93909)

Name: Anti-LBP antibody (221-270 aa) (STJ93909)
SKU: STJ93909
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenThe antiserum was produced against synthesized peptide derived from the human LBP at the amino acid range 221-270

STJ93909

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Short Description	Rabbit polyclonal anti-Lipopolysaccharide-binding protein (221-270 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA/IHC
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	1 mg/mL
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range	WB 1:500-2000 IHC-P 1:50-300 ELISA 2000-20000
Formulation	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	LBP
Gene ID	3929
Uniprot ID	LBP_HUMAN
Immunogen	The antiserum was produced against synthesized peptide derived from the human LBP at the amino acid range 221-270
Immunogen Region	221-270 aa
Specificity	LBP Polyclonal Antibody detects endogenous levels of LBP protein.

Function	Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide.
Protein Name	Lipopolysaccharide-Binding Protein Lbp
Database Links	Reactome: R-HSA-166016 Reactome: R-HSA-166020 Reactome: R-HSA-5686938 Reactome: R-HSA-6785807
Cellular Localisation	Secreted Cytoplasmic Granule Membrane Membrane-Associated In Polymorphonuclear Leukocytes (Pmn) Granules
Alternative Antibody Names	Anti-Lipopolysaccharide-Binding Protein antibody Anti-Lbp antibody Anti-LBP antibody

Information sourced from Uniprot.org