Host: |
Rabbit |
Applications: |
WB/ELISA/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Lipopolysaccharide-binding protein (221-270 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
LBP |
Gene ID: |
3929 |
Uniprot ID: |
LBP_HUMAN |
Immunogen Region: |
221-270 aa |
Specificity: |
LBP Polyclonal Antibody detects endogenous levels of LBP protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human LBP at the amino acid range 221-270 |
Function | Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide. |
Protein Name | Lipopolysaccharide-Binding ProteinLbp |
Database Links | Reactome: R-HSA-166016Reactome: R-HSA-166020Reactome: R-HSA-5686938Reactome: R-HSA-6785807 |
Cellular Localisation | SecretedCytoplasmic Granule MembraneMembrane-Associated In Polymorphonuclear Leukocytes (Pmn) Granules |
Alternative Antibody Names | Anti-Lipopolysaccharide-Binding Protein antibodyAnti-Lbp antibodyAnti-LBP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance