Anti-LAT2 antibody (80-160 aa) (STJ190135)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 80-160
General Information
| Short Description | Rabbit polyclonal anti-Linker for activation of T-cells family member 2 (80-160 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LAT2 |
| Gene ID | 7462 |
| Uniprot ID | NTAL_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 80-160 |
| Immunogen Region | 80-160 aa |
| Specificity | NTAL Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Phosphorylated on tyrosines following cross-linking of BCR in B-cells, FCGR1 in myeloid cells, or FCER1 in mast cells.which induces the recruitment of GRB2. May be polyubiquitinated. |
| Function | Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2. |
| Protein Name | Linker For Activation Of T-Cells Family Member 2Linker For Activation Of B-CellsMembrane-Associated Adapter MoleculeNon-T-Cell Activation LinkerWilliams-Beuren Syndrome Chromosomal Region 15 ProteinWilliams-Beuren Syndrome Chromosomal Region 5 Protein |
| Database Links | Reactome: R-HSA-2730905 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Iii Membrane ProteinPresent In Lipid Rafts |
| Alternative Antibody Names | Anti-Linker For Activation Of T-Cells Family Member 2 antibodyAnti-Linker For Activation Of B-Cells antibodyAnti-Membrane-Associated Adapter Molecule antibodyAnti-Non-T-Cell Activation Linker antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 15 Protein antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 5 Protein antibodyAnti-LAT2 antibodyAnti-LAB antibodyAnti-NTAL antibodyAnti-WBS15 antibodyAnti-WBSCR15 antibodyAnti-WBSCR5 antibodyAnti-HSPC046 antibody |
Information sourced from Uniprot.org