| Host: | Rabbit |
| Applications: | WB/IF/ICC/IP/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:3000IF/ICC:1:50-1:200IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirement |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LASP1 |
| Gene ID: | 3927 |
| Uniprot ID: | LASP1_HUMAN |
| Immunogen Region: | 130-205 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-205 of human LASP1 (NP_006139.1). |
| Immunogen Sequence: | RMGPSGGEGMEPERRDSQDG SSYRRPLEQQQPHHIPTSAP VYQQPQQQPVAQSYGGYKEP AAPVSIQRSAPGGGGK |
| Function | Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types. |
| Protein Name | Lim And Sh3 Domain Protein 1Lasp-1Metastatic Lymph Node Gene 50 ProteinMln 50 |
| Cellular Localisation | CytoplasmCell CortexCytoskeletonAssociated With The F-Actin Rich Cortical Cytoskeleton |
| Alternative Antibody Names | Anti-Lim And Sh3 Domain Protein 1 antibodyAnti-Lasp-1 antibodyAnti-Metastatic Lymph Node Gene 50 Protein antibodyAnti-Mln 50 antibodyAnti-LASP1 antibodyAnti-MLN50 antibody |
Information sourced from Uniprot.org