Anti-LAP3 antibody [R31-3H-7] (STJA0035649)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human LAP3
General Information
| Short Description | Rabbit monoclonal anti-LAP3 for use in WB and IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R31-3H-7 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:100-1:200 |
| Formulation | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | LAP3 |
| Gene ID | 51056 |
| Uniprot ID | AMPL_HUMAN |
| Immunogen | A synthesized peptide derived from human LAP3 |
Additional Info
| Function | Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status. |
| Protein Name | Cytosol AminopeptidaseCysteinylglycine-S-Conjugate DipeptidaseLeucine Aminopeptidase 3Lap-3Leucyl AminopeptidasePeptidase SProline AminopeptidaseProlyl Aminopeptidase |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Cytosol Aminopeptidase antibodyAnti-Cysteinylglycine-S-Conjugate Dipeptidase antibodyAnti-Leucine Aminopeptidase 3 antibodyAnti-Lap-3 antibodyAnti-Leucyl Aminopeptidase antibodyAnti-Peptidase S antibodyAnti-Proline Aminopeptidase antibodyAnti-Prolyl Aminopeptidase antibodyAnti-LAP3 antibodyAnti-LAPEP antibodyAnti-PEPS antibody |
Information sourced from Uniprot.org