Anti-LAMC1 antibody (1030-1608) (STJ118460)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LAMC1 (1030-1608) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LAMC1 |
| Gene ID | 3915 |
| Uniprot ID | LAMC1_HUMAN |
| Immunogen Region | 1030-1608 |
| Immunogen Sequence | ECPACYRLVKDKVADHRVKL QELESLIANLGTGDEMVTDQ AFEDRLKEAEREVMDLLREA QDVKDVDQNLMDRLQRVNNT LSSQISRLQNIRNTIEETGN LAEQARAHVENTERLIEIAS RELEKAKVAAANVSVTQPES TGDPNNMTLLAEEARKLAER HKQEADDIVRVAKTANDTST EAYNLLLRTLAGENQTAFEI EELNRKYEQAKNISQDLEKQ AARVHEEAKRAGDKAVEIY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1030-1275 of human LAMC1 (NP_002284.3). |
Additional Info
| Tissue Specificity | Found in the basement membranes (major component). |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| Protein Name | Laminin Subunit Gamma-1Laminin B2 ChainLaminin-1 Subunit GammaLaminin-10 Subunit GammaLaminin-11 Subunit GammaLaminin-2 Subunit GammaLaminin-3 Subunit GammaLaminin-4 Subunit GammaLaminin-6 Subunit GammaLaminin-7 Subunit GammaLaminin-8 Subunit GammaLaminin-9 Subunit GammaS-Laminin Subunit GammaS-Lam Gamma |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-373760Reactome: R-HSA-381426Reactome: R-HSA-8874081Reactome: R-HSA-8957275Reactome: R-HSA-9619665Reactome: R-HSA-9913351 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement Membrane |
| Alternative Antibody Names | Anti-Laminin Subunit Gamma-1 antibodyAnti-Laminin B2 Chain antibodyAnti-Laminin-1 Subunit Gamma antibodyAnti-Laminin-10 Subunit Gamma antibodyAnti-Laminin-11 Subunit Gamma antibodyAnti-Laminin-2 Subunit Gamma antibodyAnti-Laminin-3 Subunit Gamma antibodyAnti-Laminin-4 Subunit Gamma antibodyAnti-Laminin-6 Subunit Gamma antibodyAnti-Laminin-7 Subunit Gamma antibodyAnti-Laminin-8 Subunit Gamma antibodyAnti-Laminin-9 Subunit Gamma antibodyAnti-S-Laminin Subunit Gamma antibodyAnti-S-Lam Gamma antibodyAnti-LAMC1 antibodyAnti-LAMB2 antibody |
Information sourced from Uniprot.org