| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LAMC1 |
| Gene ID: | 3915 |
| Uniprot ID: | LAMC1_HUMAN |
| Immunogen Region: | 1030-1608 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1030-1275 of human LAMC1 (NP_002284.3). |
| Immunogen Sequence: | ECPACYRLVKDKVADHRVKL QELESLIANLGTGDEMVTDQ AFEDRLKEAEREVMDLLREA QDVKDVDQNLMDRLQRVNNT LSSQISRLQNIRNTIEETGN LAEQARAHVENTERLIEIAS RELEKAKVAAANVSVTQPES TGDPNNMTLLAEEARKLAER HKQEADDIVRVAKTANDTST EAYNLLLRTLAGENQTAFEI EELNRKYEQAKNISQDLEKQ AARVHEEAKRAGDKAVEIY |
| Tissue Specificity | Found in the basement membranes (major component). |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| Protein Name | Laminin Subunit Gamma-1 Laminin B2 Chain Laminin-1 Subunit Gamma Laminin-10 Subunit Gamma Laminin-11 Subunit Gamma Laminin-2 Subunit Gamma Laminin-3 Subunit Gamma Laminin-4 Subunit Gamma Laminin-6 Subunit Gamma Laminin-7 Subunit Gamma Laminin-8 Subunit Gamma Laminin-9 Subunit Gamma S-Laminin Subunit Gamma S-Lam Gamma |
| Database Links | Reactome: R-HSA-1474228 Reactome: R-HSA-3000157 Reactome: R-HSA-3000171 Reactome: R-HSA-3000178 Reactome: R-HSA-373760 Reactome: R-HSA-381426 Reactome: R-HSA-8874081 Reactome: R-HSA-8957275 Reactome: R-HSA-9619665 |
| Cellular Localisation | Secreted Extracellular Space Extracellular Matrix Basement Membrane |
| Alternative Antibody Names | Anti-Laminin Subunit Gamma-1 antibody Anti-Laminin B2 Chain antibody Anti-Laminin-1 Subunit Gamma antibody Anti-Laminin-10 Subunit Gamma antibody Anti-Laminin-11 Subunit Gamma antibody Anti-Laminin-2 Subunit Gamma antibody Anti-Laminin-3 Subunit Gamma antibody Anti-Laminin-4 Subunit Gamma antibody Anti-Laminin-6 Subunit Gamma antibody Anti-Laminin-7 Subunit Gamma antibody Anti-Laminin-8 Subunit Gamma antibody Anti-Laminin-9 Subunit Gamma antibody Anti-S-Laminin Subunit Gamma antibody Anti-S-Lam Gamma antibody Anti-LAMC1 antibody Anti-LAMB2 antibody |
Information sourced from Uniprot.org