| Short Description : | Rabbit polyclonal anti-Laminin subunit alpha-5 (2381-2430 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC-P 1:100-300ELISA 1:20000IF 1:100-300 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LAMA5 |
| Gene ID: | 3911 |
| Uniprot ID: | LAMA5_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human LAMA5 at the amino acid range 2381-2430 |
| Immunogen Region: | 2381-2430 aa |
| Specificity: | Laminin Alpha-5 Polyclonal Antibody detects endogenous levels of Laminin Alpha-5 protein. |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Plays a role in the regulation of skeletogenesis, through a mechanism that involves integrin-mediated signaling and PTK2B/PYK2. |
| Protein Name | Laminin Subunit Alpha-5Laminin-10 Subunit AlphaLaminin-11 Subunit AlphaLaminin-15 Subunit Alpha |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-6785807Reactome: R-HSA-8874081Reactome: R-HSA-9913351 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Component |
| Alternative Antibody Names | Anti-Laminin Subunit Alpha-5 antibodyAnti-Laminin-10 Subunit Alpha antibodyAnti-Laminin-11 Subunit Alpha antibodyAnti-Laminin-15 Subunit Alpha antibodyAnti-LAMA5 antibodyAnti-KIAA0533 antibodyAnti-KIAA1907 antibody |
Information sourced from Uniprot.org
