Anti-LAMA5 antibody (2381-2430 aa) (STJ93892)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human LAMA5 at the amino acid range 2381-2430
General Information
| Short Description | Rabbit polyclonal anti-Laminin subunit alpha-5 (2381-2430 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC-P 1:100-300ELISA 1:20000IF 1:100-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LAMA5 |
| Gene ID | 3911 |
| Uniprot ID | LAMA5_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human LAMA5 at the amino acid range 2381-2430 |
| Immunogen Region | 2381-2430 aa |
| Specificity | Laminin Alpha-5 Polyclonal Antibody detects endogenous levels of Laminin Alpha-5 protein. |
Additional Info
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Plays a role in the regulation of skeletogenesis, through a mechanism that involves integrin-mediated signaling and PTK2B/PYK2. |
| Protein Name | Laminin Subunit Alpha-5Laminin-10 Subunit AlphaLaminin-11 Subunit AlphaLaminin-15 Subunit Alpha |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-6785807Reactome: R-HSA-8874081Reactome: R-HSA-9913351 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Component |
| Alternative Antibody Names | Anti-Laminin Subunit Alpha-5 antibodyAnti-Laminin-10 Subunit Alpha antibodyAnti-Laminin-11 Subunit Alpha antibodyAnti-Laminin-15 Subunit Alpha antibodyAnti-LAMA5 antibodyAnti-KIAA0533 antibodyAnti-KIAA1907 antibody |
Information sourced from Uniprot.org