| Host: |
Goat |
| Applications: |
Pep-ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-LAMA3 (Internal) is suitable for use in ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
ELISA-antibody detection limit dilution 1:2000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
LAMA3 |
| Gene ID: |
3909 |
| Uniprot ID: |
LAMA3_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_937762.1 |
| Specificity: |
This antibody is expected to recognise isoform 1 (NP_937762.1) only. |
| Immunogen Sequence: |
NNQCHSSHKRRTK |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes. |
| Protein Name | Laminin Subunit Alpha-3Epiligrin 170 Kda SubunitE170Epiligrin Subunit AlphaKalinin Subunit AlphaLaminin-5 Subunit AlphaLaminin-6 Subunit AlphaLaminin-7 Subunit AlphaNicein Subunit Alpha |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-2022090Reactome: R-HSA-2214320Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-446107Reactome: R-HSA-8874081 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Component |
| Alternative Antibody Names | Anti-Laminin Subunit Alpha-3 antibodyAnti-Epiligrin 170 Kda Subunit antibodyAnti-E170 antibodyAnti-Epiligrin Subunit Alpha antibodyAnti-Kalinin Subunit Alpha antibodyAnti-Laminin-5 Subunit Alpha antibodyAnti-Laminin-6 Subunit Alpha antibodyAnti-Laminin-7 Subunit Alpha antibodyAnti-Nicein Subunit Alpha antibodyAnti-LAMA3 antibodyAnti-LAMNA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
