• Whole cell lysates were separated by 12% SDS-PAGE, and the membrane was blotted with anti-CK7 (ABT437) antibody. The HRP-conjugated Goat anti- mouse IgG (H + L) antibody was used to detect the antibody. Lane 1: HelaPredicted band size: 51kDaObserved band size: 51kDa
  • Human liver tissue was stained with Anti-Cytokeratin 7 (ABT437) Antibody

Anti-KRT7 antibody (350-469 aa) [ABT437] (STJ196725)

SKU:
STJ196725

£168.00 - £226.00
Current Stock:
Host: Mouse
Applications: IHC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Keratin, type II cytoskeletal 7 (350-469 aa) is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality: Monoclonal
Clone ID: ABT437
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: Liquid in PBS pH7.2, 0.03% Proclin 300, with stabilizing protein.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: IHC-P 1:200-400
WB 500-1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KRT7
Gene ID: 3855
Uniprot ID: K2C7_HUMAN
Immunogen Region: 350-469 aa
Specificity: The antibody can specifically recognize human CK7 protein, and shows no cross reaction with CK1, 4, 5, 6, 8, 10, 14, 17, 18, 19, 20. In western blotting of Hela, A431, A549 and Hela cell lysates, the
Immunogen: Synthesized peptide derived from the human Cytokeratin 7 at the amino acid range 350-469
Post Translational Modifications Arg-20 is dimethylated, probably to asymmetric dimethylarginine.
Function Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Protein Name Keratin - Type Ii Cytoskeletal 7
Cytokeratin-7
Ck-7
Keratin-7
K7
Sarcolectin
Type-Ii Keratin Kb7
Database Links Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Keratin - Type Ii Cytoskeletal 7 antibody
Anti-Cytokeratin-7 antibody
Anti-Ck-7 antibody
Anti-Keratin-7 antibody
Anti-K7 antibody
Anti-Sarcolectin antibody
Anti-Type-Ii Keratin Kb7 antibody
Anti-KRT7 antibody
Anti-SCL antibody

Information sourced from Uniprot.org

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