Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-KRT7 (230-469) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
KRT7 |
Gene ID: |
3855 |
Uniprot ID: |
K2C7_HUMAN |
Immunogen Region: |
230-469 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 230-469 of human Cytokeratin 7 (Cytokeratin 7 (KRT7) ) (NP_005547.3). |
Immunogen Sequence: |
ETELTELQSQISDTSVVLSM DNSRSLDLDGIIAEVKAQYE EMAKCSRAEAEAWYQTKFET LQAQAGKHGDDLRNTRNEIS EMNRAIQRLQAEIDNIKNQR AKLEAAIAEAEERGELALKD ARAKQEELEAALQRGKQDMA RQLREYQELMSVKLALDIEI ATYRKLLEGEESRLAGDGVG AVNISVMNSTGGSSSGGGIG LTLGGTMGSNALSFSSSAGP GLLKAYSIRTASASRRSAR |
Tissue Specificity | Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus. |
Post Translational Modifications | Arg-20 is dimethylated, probably to asymmetric dimethylarginine. |
Function | Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). |
Protein Name | Keratin - Type Ii Cytoskeletal 7Cytokeratin-7Ck-7Keratin-7K7SarcolectinType-Ii Keratin Kb7 |
Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 7 antibodyAnti-Cytokeratin-7 antibodyAnti-Ck-7 antibodyAnti-Keratin-7 antibodyAnti-K7 antibodyAnti-Sarcolectin antibodyAnti-Type-Ii Keratin Kb7 antibodyAnti-KRT7 antibodyAnti-SCL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance