| Host: | Mouse |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Keratin, type II cytoskeletal 6A (2-100 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | ABT052 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2ak |
| Formulation: | Liquid in PBS pH7.2, 0.03% Proclin 300, with stabilizing protein. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IHC-P 1:200-400WB 500-1000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KRT6A |
| Gene ID: | 3853 |
| Uniprot ID: | K2C6A_HUMAN |
| Immunogen Region: | 2-100 aa |
| Specificity: | The antibody can specifically recognize human CK6 protein, and shows no cross reaction with CK5. In western blotting of Hela, A431, A549 and HEK293 cell lysates, the antibody can label a 56 kDa band c |
| Immunogen: | Synthesized peptide derived from the human Cytokeratin 6 at the amino acid range 2-100 |
| Function | Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. |
| Protein Name | Keratin - Type Ii Cytoskeletal 6aCytokeratin-6aCk-6aCytokeratin-6dCk-6dKeratin-6aK6aType-Ii Keratin Kb6Allergen Hom S 5 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 6a antibodyAnti-Cytokeratin-6a antibodyAnti-Ck-6a antibodyAnti-Cytokeratin-6d antibodyAnti-Ck-6d antibodyAnti-Keratin-6a antibodyAnti-K6a antibodyAnti-Type-Ii Keratin Kb6 antibodyAnti-Allergen Hom S 5 antibodyAnti-KRT6A antibodyAnti-K6A antibodyAnti-KRT6D antibody |
Information sourced from Uniprot.org