Anti-KRT13 antibody (400-458 aa) [ABT057] (STJ190041)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenSynthesized peptide derived from the human Cytokeratin 13 at the amino acid range 400-458
General Information
| Short Description | Mouse monoclonal anti-Keratin, type I cytoskeletal 13 (400-458 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ABT057 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | IHC-P 1:200-400WB 500-1000 |
| Formulation | Liquid in PBS pH7.2, 0.03% Proclin 300, with stabilizing protein. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KRT13 |
| Gene ID | 3860 |
| Uniprot ID | K1C13_HUMAN |
| Immunogen | Synthesized peptide derived from the human Cytokeratin 13 at the amino acid range 400-458 |
| Immunogen Region | 400-458 aa |
| Specificity | The antibody can specifically recognize human CK13 protein. In western blotting of A431 cell lysate, the antibody can label a 50 kDa band corresponding to CK13. |
Additional Info
| Post Translational Modifications | O-glycosylated.glycans consist of single N-acetylglucosamine residues. |
| Function | Type 1 keratin (Probable). Maintains postnatal tongue mucosal cell homeostasis and tissue organization in response to mechanical stress, potentially via regulation of the G1/S phase cyclins CCNE1 and CCNE2. |
| Protein Name | Keratin - Type I Cytoskeletal 13Cytokeratin-13Ck-13Keratin-13K13 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Keratin - Type I Cytoskeletal 13 antibodyAnti-Cytokeratin-13 antibodyAnti-Ck-13 antibodyAnti-Keratin-13 antibodyAnti-K13 antibodyAnti-KRT13 antibody |
Information sourced from Uniprot.org