| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:100IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KRT13 |
| Gene ID: | 3860 |
| Uniprot ID: | K1C13_HUMAN |
| Immunogen Region: | 269-458 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 269-458 of human Cytokeratin 13 (Cytokeratin 13 (KRT13) ) (NP_705694.2). |
| Immunogen Sequence: | DLTRVLAEMREQYEAMAERN RRDAEEWFHAKSAELNKEVS TNTAMIQTSKTEITELRRTL QGLEIELQSQLSMKAGLENT VAETECRYALQLQQIQGLIS SIEAQLSELRSEMECQNQEY KMLLDIKTRLEQEIATYRSL LEGQDAKMIGFPSSAGSVSP RSTSVTTTSSASVTTTSNAS GRRTSDVRRP |
| Tissue Specificity | Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta. |
| Post Translational Modifications | O-glycosylated.glycans consist of single N-acetylglucosamine residues. |
| Function | Type 1 keratin (Probable). Maintains postnatal tongue mucosal cell homeostasis and tissue organization in response to mechanical stress, potentially via regulation of the G1/S phase cyclins CCNE1 and CCNE2. |
| Protein Name | Keratin - Type I Cytoskeletal 13Cytokeratin-13Ck-13Keratin-13K13 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Alternative Antibody Names | Anti-Keratin - Type I Cytoskeletal 13 antibodyAnti-Cytokeratin-13 antibodyAnti-Ck-13 antibodyAnti-Keratin-13 antibodyAnti-K13 antibodyAnti-KRT13 antibody |
Information sourced from Uniprot.org