| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KRR1 |
| Gene ID: | 11103 |
| Uniprot ID: | KRR1_HUMAN |
| Immunogen Region: | 1-381 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-381 of human KRR1 (NP_008974.5). |
| Immunogen Sequence: | MASPSLERPEKGAGKSEFRN QKPKPENQDESELLTVPDGW KEPAFSKEDNPRGLLEESSF ATLFPKYREAYLKECWPLVQ KALNEHHVNATLDLIEGSMT VCTTKKTFDPYIIIRARDLI KLLARSVSFEQAVRILQDDV ACDIIKIGSLVRNKERFVKR RQRLIGPKGSTLKALELLTN CYIMVQGNTVSAIGPFSGLK EVRKVVLDTMKNIHPIYNIK SLMIKRELAKDSELRSQSW |
| Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. |
| Protein Name | Krr1 Small Subunit Processome Component Homolog Hiv-1 Rev-Binding Protein 2 Krr-R Motif-Containing Protein 1 Rev-Interacting Protein 1 Rip-1 |
| Database Links | Reactome: R-HSA-6790901 Reactome: R-HSA-6791226 |
| Cellular Localisation | Nucleus Nucleolus Cytoplasm (Microbial Infection) Translocates From Cytoplasm To Nucleus After Exposure To Hiv-1 Virus Or Hiv-1 Protein Vpr Or Induction By Hydrocortisone And Dexamethasone In The Absence Of Hiv-1 Protein Vpr |
| Alternative Antibody Names | Anti-Krr1 Small Subunit Processome Component Homolog antibody Anti-Hiv-1 Rev-Binding Protein 2 antibody Anti-Krr-R Motif-Containing Protein 1 antibody Anti-Rev-Interacting Protein 1 antibody Anti-Rip-1 antibody Anti-KRR1 antibody Anti-HRB2 antibody |
Information sourced from Uniprot.org