• Confocal Immunofluorescent analysis of U2OS cells using KRR1 Rabbit polyclonal antibody (STJ116243) at dilution of 1:100 (40x lens) (red). Beta-Actin (AC004: ACTB Mouse mAb) for Cytoskeleton staining (green) , DAPI for nuclear staining (blue).
  • Confocal Immunofluorescent analysis of U2OS cells using KRR1 Rabbit polyclonal antibody (STJ116243) at dilution of 1:100 (40x lens) (red). Vimentin (A19607: Vimentin Rabbit mAb) for Cytoskeleton staining (green) , DAPI for nuclear staining (blue).
  • Confocal immunofluorescence analysis of U2OS cells using KRR1 Rabbit polyclonal antibody (STJ116243) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Western blot analysis of various lysates using KRR1 Rabbit polyclonal antibody (STJ116243) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-KRR1 antibody (1-381) (STJ116243)

SKU:
STJ116243

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-KRR1 (1-381) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KRR1
Gene ID: 11103
Uniprot ID: KRR1_HUMAN
Immunogen Region: 1-381
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-381 of human KRR1 (NP_008974.5).
Immunogen Sequence: MASPSLERPEKGAGKSEFRN QKPKPENQDESELLTVPDGW KEPAFSKEDNPRGLLEESSF ATLFPKYREAYLKECWPLVQ KALNEHHVNATLDLIEGSMT VCTTKKTFDPYIIIRARDLI KLLARSVSFEQAVRILQDDV ACDIIKIGSLVRNKERFVKR RQRLIGPKGSTLKALELLTN CYIMVQGNTVSAIGPFSGLK EVRKVVLDTMKNIHPIYNIK SLMIKRELAKDSELRSQSW
Function Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Protein Name Krr1 Small Subunit Processome Component Homolog
Hiv-1 Rev-Binding Protein 2
Krr-R Motif-Containing Protein 1
Rev-Interacting Protein 1
Rip-1
Database Links Reactome: R-HSA-6790901
Reactome: R-HSA-6791226
Cellular Localisation Nucleus
Nucleolus
Cytoplasm
(Microbial Infection) Translocates From Cytoplasm To Nucleus After Exposure To Hiv-1 Virus Or Hiv-1 Protein Vpr Or Induction By Hydrocortisone And Dexamethasone In The Absence Of Hiv-1 Protein Vpr
Alternative Antibody Names Anti-Krr1 Small Subunit Processome Component Homolog antibody
Anti-Hiv-1 Rev-Binding Protein 2 antibody
Anti-Krr-R Motif-Containing Protein 1 antibody
Anti-Rev-Interacting Protein 1 antibody
Anti-Rip-1 antibody
Anti-KRR1 antibody
Anti-HRB2 antibody

Information sourced from Uniprot.org

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