Anti-KLRG1 antibody [DM184] (STJA0038153)

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STJA0038153-100
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Host: Rabbit
Applications: FC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-KLRG1 for use in FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : DM184
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purification: Affinity Chromatography
Dilution Range: FC 1:50-1:100
ELISA 1:10000
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: KLRG1
Gene ID: 10219
Uniprot ID: KLRG1_HUMAN
Immunogen: Recombinant human KLRG1 protein
Tissue Specificity Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.
Function Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
Protein Name Killer Cell Lectin-Like Receptor Subfamily G Member 1
C-Type Lectin Domain Family 15 Member A
Itim-Containing Receptor Mafa-L
Mafa-Like Receptor
Mast Cell Function-Associated Antigen
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Killer Cell Lectin-Like Receptor Subfamily G Member 1 antibody
Anti-C-Type Lectin Domain Family 15 Member A antibody
Anti-Itim-Containing Receptor Mafa-L antibody
Anti-Mafa-Like Receptor antibody
Anti-Mast Cell Function-Associated Antigen antibody
Anti-KLRG1 antibody
Anti-CLEC15A antibody
Anti-MAFA antibody
Anti-MAFAL antibody

Information sourced from Uniprot.org