Anti-KLRG1 antibody {ABflo® 647} (STJ11108910)

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STJ11108910
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Short Description :Rabbit monoclonal KLRG1 antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Isotype:IgG
Conjugation:ABflo® 647
Purification:Affinity purification
Dilution Range:FC, 5 Mu l per 10^6 cells in 100 Mu l volume
Formulation:PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis) , pH 7.3.
Storage Instruction:Store at 4°C for up to 1 year from the date of receipt. Do not freeze.
Gene Symbol:KLRG1
Gene ID:10219
Uniprot ID:KLRG1_HUMAN
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tissue Specificity Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.
Function Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
Protein Name Killer Cell Lectin-Like Receptor Subfamily G Member 1
C-Type Lectin Domain Family 15 Member A
Itim-Containing Receptor Mafa-L
Mafa-Like Receptor
Mast Cell Function-Associated Antigen
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Killer Cell Lectin-Like Receptor Subfamily G Member 1 antibody
Anti-C-Type Lectin Domain Family 15 Member A antibody
Anti-Itim-Containing Receptor Mafa-L antibody
Anti-Mafa-Like Receptor antibody
Anti-Mast Cell Function-Associated Antigen antibody
Anti-KLRG1 antibody
Anti-CLEC15A antibody
Anti-MAFA antibody
Anti-MAFAL antibody

Information sourced from Uniprot.org