Anti-KLK3 antibody [IHC654] (STJA0042021)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenHuman PSA protein.
General Information
| Short Description | Mouse monoclonal anti-KLK3 for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-p |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | IHC654 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Dilution Range | 1:100-1:200 |
| Formulation | Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1 year. Do not freeze. |
Target Information
| Gene Symbol | KLKB1 |
| Gene ID | 3818 |
| Uniprot ID | KLKB1_HUMAN |
| Immunogen | Human PSA protein. |
| Specificity | Tested and validated on prostate, prostate carcinoma tissue. |
Additional Info
| Tissue Specificity | Found in plasma (at protein level). |
| Function | Participates in the surface-dependent activation of blood coagulation. Activates, in a reciprocal reaction, coagulation factor XII/F12 after binding to negatively charged surfaces. Releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. |
| Protein Name | Plasma KallikreinFletcher FactorKininogeninPlasma PrekallikreinPkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain |
| Database Links | Reactome: R-HSA-140837Reactome: R-HSA-1592389Reactome: R-HSA-9657688Reactome: R-HSA-9657689 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Plasma Kallikrein antibodyAnti-Fletcher Factor antibodyAnti-Kininogenin antibodyAnti-Plasma Prekallikrein antibodyAnti-Pkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain antibodyAnti-KLKB1 antibodyAnti-KLK3 antibody |
Information sourced from Uniprot.org