Anti-KLK3 antibody [IHC654] (STJA0042021)

SKU:
STJA0042021
£115.50 - £285.50
Processing The item has been added

Host: Mouse
Applications: IHC-p
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-KLK3 for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : IHC654
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Dilution Range: 1:100-1:200
Storage Instruction: Store at 2-8°C for up to 1 year. Do not freeze.
Gene Symbol: KLKB1
Gene ID: 3818
Uniprot ID: KLKB1_HUMAN
Specificity: Tested and validated on prostate, prostate carcinoma tissue.
Immunogen: Human PSA protein.
Tissue Specificity Found in plasma (at protein level).
Function Participates in the surface-dependent activation of blood coagulation. Activates, in a reciprocal reaction, coagulation factor XII/F12 after binding to negatively charged surfaces. Releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
Protein Name Plasma Kallikrein
Fletcher Factor
Kininogenin
Plasma Prekallikrein
Pkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain
Database Links Reactome: R-HSA-140837
Reactome: R-HSA-1592389
Reactome: R-HSA-9657688
Reactome: R-HSA-9657689
Cellular Localisation Secreted
Alternative Antibody Names Anti-Plasma Kallikrein antibody
Anti-Fletcher Factor antibody
Anti-Kininogenin antibody
Anti-Plasma Prekallikrein antibody
Anti-Pkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain antibody
Anti-KLKB1 antibody
Anti-KLK3 antibody

Information sourced from Uniprot.org