| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KLHL11 |
| Gene ID: | 55175 |
| Uniprot ID: | KLH11_HUMAN |
| Immunogen Region: | 16-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 16-300 of human KLHL11 (NP_060613.1). |
| Immunogen Sequence: | ASLQVLEMESMETAAAGSAG LAAEVRGSGTVDFGPGPGIS AMEASGGDPGPEAEDFECSS HCSELSWRQNEQRRQGLFCD ITLCFGGAGGREFRAHRSVL AAATEYFTPLLSGQFSESRS GRVEMRKWSSEPGPEPDTVE AVIEYMYTGRIRVSTGSVHE VLELADRFLLIRLKEFCGEF LKKKLHLSNCVAIHSLAHMY TLSQLALKAADMIRRNFHKV IQDEEFYTLPFHLIRDWLS |
| Function | Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. |
| Protein Name | Kelch-Like Protein 11 |
| Database Links | Reactome: R-HSA-8951664 Reactome: R-HSA-983168 |
| Alternative Antibody Names | Anti-Kelch-Like Protein 11 antibody Anti-KLHL11 antibody |
Information sourced from Uniprot.org