• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-KLF8 antibody (191-240 aa) (STJ93849)

SKU:
STJ93849

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Krueppel-like factor 8 (191-240 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KLF8
Gene ID: 11279
Uniprot ID: KLF8_HUMAN
Immunogen Region: 191-240 aa
Specificity: KLF8 Polyclonal Antibody detects endogenous levels of KLF8 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human KLF8 at the amino acid range 191-240
Post Translational Modifications Sumoylation at Lys-67 represses transcriptional activity and reduces cell cycle progression into the G(1) phase. Has no effect on subcellular location.
Function Transcriptional repressor and activator. Binds to CACCC-boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK).
Protein Name Krueppel-Like Factor 8
Basic Krueppel-Like Factor 3
Zinc Finger Protein 741
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Krueppel-Like Factor 8 antibody
Anti-Basic Krueppel-Like Factor 3 antibody
Anti-Zinc Finger Protein 741 antibody
Anti-KLF8 antibody
Anti-BKLF3 antibody
Anti-ZNF741 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance