| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:1000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KLF5 |
| Gene ID: | 688 |
| Uniprot ID: | KLF5_HUMAN |
| Immunogen Region: | 1-250 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human KLF5 (NP_001721.2). |
| Immunogen Sequence: | MATRVLSMSARLGPVPQPPA PQDEPVFAQLKPVLGAANPA RDAALFPGEELKHAHHRPQA QPAPAQAPQPAQPPATGPRL PPEDLVQTRCEMEKYLTPQL PPVPIIPEHKKYRRDSASVV DQFFTDTEGLPYSINMNVFL PDITHLRTGLYKSQRPCVTH IKTEPVAIFSHQSETTAPPP APTQALPEFTSIFSSHQTAA PEVNNIFIKQELPTPDLHLS VPTQQGHLYQLLNTPDLDM |
| Tissue Specificity | Expressed only in testis and placenta. |
| Post Translational Modifications | Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein. Deubiquitinated by ATXN3L. |
| Function | Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes. |
| Protein Name | Krueppel-Like Factor 5 Basic Transcription Element-Binding Protein 2 Bte-Binding Protein 2 Colon Krueppel-Like Factor Gc-Box-Binding Protein 2 Intestinal-Enriched Krueppel-Like Factor Transcription Factor Bteb2 |
| Database Links | Reactome: R-HSA-381340 Reactome: R-HSA-9616222 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 5 antibody Anti-Basic Transcription Element-Binding Protein 2 antibody Anti-Bte-Binding Protein 2 antibody Anti-Colon Krueppel-Like Factor antibody Anti-Gc-Box-Binding Protein 2 antibody Anti-Intestinal-Enriched Krueppel-Like Factor antibody Anti-Transcription Factor Bteb2 antibody Anti-KLF5 antibody Anti-BTEB2 antibody Anti-CKLF antibody Anti-IKLF antibody |
Information sourced from Uniprot.org