| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FKLF (N-Term) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS + 0.02% NaN3 |
| Purification: |
Antigen Affinity Purified |
| Dilution Range: |
WB 1:500-1:1000IHCICCIP |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KLF11 |
| Gene ID: |
8462 |
| Uniprot ID: |
KLF11_HUMAN |
| Immunogen Region: |
N-Term |
| Specificity: |
Reacts with the N-terminal region of human FKLF protein. Tested in human fetal liver tissue and the K562 erythroid cell line. Low levels of protein seen in other adult and fetal tissues or non-erythroid cell lines. |
| Immunogen: |
Synthetic peptide corresponding to amino acids from the N-terminal region of human FKLF protein |
| Function | Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis. |
| Protein Name | Krueppel-Like Factor 11Transforming Growth Factor-Beta-Inducible Early Growth Response Protein 2Tgfb-Inducible Early Growth Response Protein 2Tieg-2 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 11 antibodyAnti-Transforming Growth Factor-Beta-Inducible Early Growth Response Protein 2 antibodyAnti-Tgfb-Inducible Early Growth Response Protein 2 antibodyAnti-Tieg-2 antibodyAnti-KLF11 antibodyAnti-FKLF antibodyAnti-TIEG2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
