| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KLF11 |
| Gene ID: | 8462 |
| Uniprot ID: | KLF11_HUMAN |
| Immunogen Region: | 13-107 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 13-107 of human KLF11 (NP_003588.1). |
| Immunogen Sequence: | RAVDIMDICESILERKRHDS ERSTCSILEQTDMEAVEALV CMSSWGQRSQKGDLLRIRPL TPVSDSGDVTTTVHMDAATP ELPKDFHSLSTLCIT |
| Tissue Specificity | Ubiquitous. Higher expression in erythroid cells. |
| Function | Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis. |
| Protein Name | Krueppel-Like Factor 11Transforming Growth Factor-Beta-Inducible Early Growth Response Protein 2Tgfb-Inducible Early Growth Response Protein 2Tieg-2 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 11 antibodyAnti-Transforming Growth Factor-Beta-Inducible Early Growth Response Protein 2 antibodyAnti-Tgfb-Inducible Early Growth Response Protein 2 antibodyAnti-Tieg-2 antibodyAnti-KLF11 antibodyAnti-FKLF antibodyAnti-TIEG2 antibody |
Information sourced from Uniprot.org