| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KLF11 |
| Gene ID: |
8462 |
| Uniprot ID: |
KLF11_HUMAN |
| Immunogen Region: |
13-107 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 13-107 of human KLF11 (NP_003588.1). |
| Immunogen Sequence: |
RAVDIMDICESILERKRHDS ERSTCSILEQTDMEAVEALV CMSSWGQRSQKGDLLRIRPL TPVSDSGDVTTTVHMDAATP ELPKDFHSLSTLCIT |
| Tissue Specificity | Ubiquitous. Higher expression in erythroid cells. |
| Function | Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis. |
| Protein Name | Krueppel-Like Factor 11Transforming Growth Factor-Beta-Inducible Early Growth Response Protein 2Tgfb-Inducible Early Growth Response Protein 2Tieg-2 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 11 antibodyAnti-Transforming Growth Factor-Beta-Inducible Early Growth Response Protein 2 antibodyAnti-Tgfb-Inducible Early Growth Response Protein 2 antibodyAnti-Tieg-2 antibodyAnti-KLF11 antibodyAnti-FKLF antibodyAnti-TIEG2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
