| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KLC2 (1-90) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KLC2 |
| Gene ID: |
64837 |
| Uniprot ID: |
KLC2_HUMAN |
| Immunogen Region: |
1-90 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human KLC2 (NP_073733.1). |
| Immunogen Sequence: |
MAMMVFPREEKLSQDEIVLG TKAVIQGLETLRGEHRALLA PLVAPEAGEAEPGSQERCIL LRRSLEAIELGLGEAQVILA LSSHLGAVES |
| Function | Kinesin is a microtubule-associated force-producing protein that plays a role in organelle transport. The light chain functions in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (Probable). Through binding with PLEKHM2 and ARL8B, recruits kinesin-1 to lysosomes and hence direct lysosomes movement toward microtubule plus ends. |
| Protein Name | Kinesin Light Chain 2Klc 2 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-5625970Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
| Cellular Localisation | CytoplasmCytoskeletonLysosome MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Kinesin Light Chain 2 antibodyAnti-Klc 2 antibodyAnti-KLC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
