| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KLC1 (261-560) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KLC1 |
| Gene ID: |
3831 |
| Uniprot ID: |
KLC1_HUMAN |
| Immunogen Region: |
261-560 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 261-560 of human Kinesin light chain 1 (Kinesin light chain 1 (KLC1) ) (NP_005543.2). |
| Immunogen Sequence: |
LALVYRDQNKYKDAANLLND ALAIREKTLGKDHPAVAATL NNLAVLYGKRGKYKEAEPLC KRALEIREKVLGKDHPDVAK QLNNLALLCQNQGKYEEVEY YYQRALEIYQTKLGPDDPNV AKTKNNLASCYLKQGKFKQA ETLYKEILTRAHEREFGSVD DENKPIWMHAEEREECKGKQ KDGTSFGEYGGWYKACKVDS PTVTTTLKNLGALYRRQGKF EAAETLEEAAMRSRKQGLD |
| Tissue Specificity | Found in a variety of tissues. Mostly abundant in brain and spine. |
| Post Translational Modifications | Phosphorylation at Ser-460 by ERK inhibits interaction with CLSTN1 and localization to cytoplasmic vesicles. |
| Function | Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. |
| Protein Name | Kinesin Light Chain 1Klc 1 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-5625970Reactome: R-HSA-6811434Reactome: R-HSA-9725370Reactome: R-HSA-983189 |
| Cellular Localisation | Cell ProjectionGrowth ConeCytoplasmic VesicleCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Kinesin Light Chain 1 antibodyAnti-Klc 1 antibodyAnti-KLC1 antibodyAnti-KLC antibodyAnti-KNS2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
