Anti-KIRREL3/NEPH2 antibody [N321C/49R] (STJA0019224)

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STJA0019224
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Host: Mouse
Applications: IF/IHC/WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-KIRREL3/NEPH2 is suitable for use in Immunofluorescence, Immunohistochemistry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : N321C/49R
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: Kirrel3
Gene ID: 67703
Uniprot ID: KIRR3_MOUSE
Post Translational Modifications Undergoes proteolysis by a metalloprotease and gives rise to a soluble form.
Function Synaptic adhesion molecule required for the formation of target-specific synapses. Required for formation of target-specific synapses at hippocampal mossy fiber synapses. Required for formation of mossy fiber filopodia, the synaptic structures connecting dentate granule and GABA neurons. Probably acts as a homophilic adhesion molecule that promotes trans-cellular interactions and stabilize mossy fiber filipodia contact and subsequent synapse formation. Required for the coalescence of vomeronasal sensory neuron axons. May be involved in the hematopoietic supportive capacity of stroma cells.the secreted extracellular domain is directly responsible for supporting hematopoietic stem cells.
Protein Name Kin Of Irre-Like Protein 3
Kin Of Irregular Chiasm-Like Protein 3
Nephrin-Like Protein 2
Mkirre Cleaved Into - Processed Kin Of Irre-Like Protein 3
Database Links Reactome: R-MMU-373753
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Axon
Dendrite
Processed Kin Of Irre-Like Protein 3: Secreted
Alternative Antibody Names Anti-Kin Of Irre-Like Protein 3 antibody
Anti-Kin Of Irregular Chiasm-Like Protein 3 antibody
Anti-Nephrin-Like Protein 2 antibody
Anti-Mkirre Cleaved Into - Processed Kin Of Irre-Like Protein 3 antibody
Anti-Kirrel3 antibody
Anti-Kiaa1867 antibody
Anti-Neph2 antibody

Information sourced from Uniprot.org