| Post Translational Modifications | Undergoes proteolysis by a metalloprotease and gives rise to a soluble form. |
| Function | Synaptic adhesion molecule required for the formation of target-specific synapses. Required for formation of target-specific synapses at hippocampal mossy fiber synapses. Required for formation of mossy fiber filopodia, the synaptic structures connecting dentate granule and GABA neurons. Probably acts as a homophilic adhesion molecule that promotes trans-cellular interactions and stabilize mossy fiber filipodia contact and subsequent synapse formation. Required for the coalescence of vomeronasal sensory neuron axons. May be involved in the hematopoietic supportive capacity of stroma cells.the secreted extracellular domain is directly responsible for supporting hematopoietic stem cells. |
| Protein Name | Kin Of Irre-Like Protein 3Kin Of Irregular Chiasm-Like Protein 3Nephrin-Like Protein 2 Cleaved Into - Processed Kin Of Irre-Like Protein 3 |
| Database Links | Reactome: R-HSA-373753 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinProcessed Kin Of Irre-Like Protein 3: Secreted |
| Alternative Antibody Names | Anti-Kin Of Irre-Like Protein 3 antibodyAnti-Kin Of Irregular Chiasm-Like Protein 3 antibodyAnti-Nephrin-Like Protein 2 Cleaved Into - Processed Kin Of Irre-Like Protein 3 antibodyAnti-KIRREL3 antibodyAnti-KIAA1867 antibodyAnti-NEPH2 antibodyAnti-UNQ5923 antibodyAnti-PRO4502 antibodyAnti-PRO19814 antibody |
Information sourced from Uniprot.org
