| Host: |
Rabbit |
| Applications: |
WB/IHC-P |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Rabbit monoclonal anti-KIFAP3 for use in WB and IHC-P in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : |
Monoclonal |
| Clone ID : |
R03-6C6 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification: |
Affinity Purified |
| Concentration: |
0.3 mg/mL |
| Dilution Range: |
WB 1:500-1:1000IHC 1:50-1:100 |
| Storage Instruction: |
Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Post Translational Modifications | Phosphorylated on tyrosine residues by SRC in vitro.this reduces the binding affinity of the protein for RAP1GDS1. |
| Function | Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Binds to the tail domain of the KIF3A/KIF3B heterodimer to form a heterotrimeric KIF3 complex and may regulate the membrane binding of this complex. |
| Protein Name | Kinesin-Associated Protein 3Kap-3Kap3Smg Gds-Associated Protein |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-2132295Reactome: R-HSA-5620924Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Kinesin-Associated Protein 3 antibodyAnti-Kap-3 antibodyAnti-Kap3 antibodyAnti-Smg Gds-Associated Protein antibodyAnti-KIFAP3 antibodyAnti-KIF3AP antibodyAnti-SMAP antibody |
Information sourced from Uniprot.org
