Western blot analysis of lysates from HeLa cells, using KIF4A Antibody. The lane on the right is blocked with the synthesized peptide.

Anti-KIF4A antibody (1171-1220 aa) (STJ93837)

SKU:
STJ93837
£48.00 - £252.00
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Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Chromosome-associated kinesin KIF4A (1171-1220 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KIF4A
Gene ID: 24137
Uniprot ID: KIF4A_HUMAN
Immunogen Region: 1171-1220 aa
Specificity: KIF4A Polyclonal Antibody detects endogenous levels of KIF4A protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human KIF4A at the amino acid range 1171-1220
Function Iron-sulfur (Fe-S) cluster binding motor protein that has a role in chromosome segregation during mitosis. Translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.
Protein Name Chromosome-Associated Kinesin Kif4a
Chromokinesin-A
Database Links Reactome: R-HSA-2132295
Reactome: R-HSA-437239
Reactome: R-HSA-6811434
Reactome: R-HSA-983189
Cellular Localisation Nucleus Matrix
Cytoplasm
Cytoskeleton
Spindle
Midbody
Chromosome
Associates With Chromosomes At All Stage Of Mitosis
Chromatin Localization Is Dependent On Iron-Sulfur Cluster Binding
In Anaphase
Associates With The Mitotic Spindle Midzone
In Telophase And Cytokinesis
Co-Localizes With Ciao2b At The Spindle Midzone And Midbody
Co-Localizes With Prc1 In Early Mitosis And At The Spindle Midzone From Anaphase B To Telophase
Does Not Localize To The Nucleolus
Alternative Antibody Names Anti-Chromosome-Associated Kinesin Kif4a antibody
Anti-Chromokinesin-A antibody
Anti-KIF4A antibody
Anti-KIF4 antibody

Information sourced from Uniprot.org

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