| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KIF2A (30-220) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KIF2A |
| Gene ID: |
3796 |
| Uniprot ID: |
KIF2A_HUMAN |
| Immunogen Region: |
30-220 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 30-220 of human KIF2A (NP_004511.2). |
| Immunogen Sequence: |
TSLNEDNESVTVEWIENGDT KGKEIDLESIFSLNPDLVPD EEIEPSPETPPPPASSAKVN KIVKNRRTVASIKNDPPSRD NRVVGSARARPSQFPEQSSS AQQNGSVSDISPVQAAKKEF GPPSRRKSNCVKEVEKLQEK REKRRLQQQELREKRAQDVD ATNPNYEIMCMIRDFRGSLD YRPLTTADPID |
| Function | Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity. |
| Protein Name | Kinesin-Like Protein Kif2aKinesin-2Hk2 |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-2132295Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-5663220Reactome: R-HSA-6811434Reactome: R-HSA-68877Reactome: R-HSA-9648025Reactome: R-HSA-983189 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindle PoleSpindleLocalized To The Spindle Microtubules And Spindle Poles From Prophase To MetaphaseEfficient Targeting To Spindle Microtubules And Spindle Poles Requires The Kinase Activity Of Plk1Recruited To Mitotic Spindles By Interaction With Psrc1 |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif2a antibodyAnti-Kinesin-2 antibodyAnti-Hk2 antibodyAnti-KIF2A antibodyAnti-KIF2 antibodyAnti-KNS2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
