| Post Translational Modifications | Phosphorylated by PLK1 at Ser-528 during mitosis, creating a docking site for PLK1 and recruiting PLK1 at central spindle. |
| Function | Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. |
| Protein Name | Kinesin-Like Protein Kif20aGg10_2Mitotic Kinesin-Like Protein 2Mklp2Rab6-Interacting Kinesin-Like ProteinRabkinesin-6 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-6811434Reactome: R-HSA-68884Reactome: R-HSA-983189 |
| Cellular Localisation | Golgi ApparatusCytoplasmCytoskeletonSpindleLocalizes To The Spindle Midzone During Anaphase And Telophase |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif20a antibodyAnti-Gg10_2 antibodyAnti-Mitotic Kinesin-Like Protein 2 antibodyAnti-Mklp2 antibodyAnti-Rab6-Interacting Kinesin-Like Protein antibodyAnti-Rabkinesin-6 antibodyAnti-KIF20A antibodyAnti-MKLP2 antibodyAnti-RAB6KIFL antibody |
Information sourced from Uniprot.org
