| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KIAA1524 (681-905) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CIP2A |
| Gene ID: |
57650 |
| Uniprot ID: |
CIP2A_HUMAN |
| Immunogen Region: |
681-905 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 681-905 of human KIAA1524 (NP_065941.2). |
| Immunogen Sequence: |
EVERKNEELSVLLKAQQVES ERAQSDIEHLFQHNRKLESV AEEHEILTKSYMELLQRNES TEKKNKDLQITCDSLNKQIE TVKKLNESLKEQNEKSIAQL IEKEEQRKEVQNQLVDREHK LANLHQKTKVQEEKIKTLQK EREDKEETIDILRKELSRTE QIRKELSIKASSLEVQKAQL EGRLEEKESLVKLQQEELNK HSHMIAMIHSLSGGKINPET VNLSI |
| Tissue Specificity | Expressed at low levels in most of the tissues. Overexpressed in head-and-neck squamous cell carcinomas (HNSCC). Present in liver cancer cells (at protein level). |
| Function | Oncoprotein that inhibits PP2A and stabilizes MYC in human malignancies. Promotes anchorage-independent cell growth and tumor formation. |
| Protein Name | Protein Cip2aCancerous Inhibitor Of Pp2aP90 Autoantigen |
| Cellular Localisation | MembraneSingle-Pass Membrane ProteinCytoplasmSlightly Concentrates In The Perinuclear Region |
| Alternative Antibody Names | Anti-Protein Cip2a antibodyAnti-Cancerous Inhibitor Of Pp2a antibodyAnti-P90 Autoantigen antibodyAnti-CIP2A antibodyAnti-KIAA1524 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
