• Western blot analysis of extracts of various cell lines, using KIAA0391 antibody (STJ26245) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 30s.

Anti-KIAA0391 antibody (314-583) (STJ26245)

SKU:
STJ26245

$151.88 - $705.38
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Host: Rabbit
Applications: WB
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-KIAA0391 (314-583) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PRORP
Gene ID: 9692
Uniprot ID: MRPP3_HUMAN
Immunogen Region: 314-583
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 314-583 of human KIAA0391 (NP_055487.2).
Immunogen Sequence: YPGESFAHSIKTWFESVPGK QWKGQFTTVRKSGQCSGCGK TIESIQLSPEEYECLKGKIM RDVIDGGDQYRKTTPQELKR FENFIKSRPPFDVVIDGLNV AKMFPKVRESQLLLNVVSQL AKRNLRLLVLGRKHMLRRSS QWSRDEMEEVQKQASCFFAD DISEDDPFLLYATLHSGNHC RFITRDLMRDHKACLPDAKT QRLFFKWQQGHQLAIVNRFP GSKLTFQRILSYDTVVQTT
Post Translational Modifications Degraded by LONP1 following mitochondrial unfolded protein response, probably leading to inhibit translation in mitochondrion.
Function Catalytic ribonuclease component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends. The presence of TRMT10C/MRPP1, HSD17B10/MRPP2 is required to catalyze tRNA molecules in their 5'-ends.
Protein Name Mitochondrial Ribonuclease P Catalytic Subunit
Mitochondrial Ribonuclease P Protein 3
Mitochondrial Rnase P Protein 3
Protein Only Rnase P Catalytic Subunit
Database Links Reactome: R-HSA-6785470
Reactome: R-HSA-6787450
Reactome: R-HSA-8868766
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-Mitochondrial Ribonuclease P Catalytic Subunit antibody
Anti-Mitochondrial Ribonuclease P Protein 3 antibody
Anti-Mitochondrial Rnase P Protein 3 antibody
Anti-Protein Only Rnase P Catalytic Subunit antibody
Anti-PRORP antibody
Anti-KIAA0391 antibody
Anti-MRPP3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance