Anti-Keratin 8 antibody [C51] (STJA0018397)

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STJA0018397-5
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Host: Mouse
Applications: IHC
Reactivity: Human
Note: FOR RESEARCH USE ONLY (RUO).
Short Description : Mouse monoclonal antibody anti-Keratin-Type Ii Cytoskeletal 8 is suitable for use in Immunohistochemistry research applications.
Clonality : Monoclonal
Clone ID : C51
Conjugation: Unconjugated
Formulation: Cell culture supernatant with 0.09% Sodium azide, and Fetal Calf Serum
Dilution Range: Please carry out application specific titration to determine the most appropriate dilution ratio.
Storage Instruction: Shipped on gel ice packs. Store at 2-8C on arrival.
Gene Symbol: KRT8
Gene ID: 3856
Uniprot ID: K2C8_HUMAN
Post Translational Modifications Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization. O-glycosylated. O-GlcNAcylation at multiple sites increases solubility, and decreases stability by inducing proteasomal degradation. O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner.
Function Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Protein Name Keratin - Type Ii Cytoskeletal 8
Cytokeratin-8
Ck-8
Keratin-8
K8
Type-Ii Keratin Kb8
Database Links Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Cellular Localisation Cytoplasm
Nucleus
Nucleoplasm
Nucleus Matrix
Alternative Antibody Names Anti-Keratin - Type Ii Cytoskeletal 8 antibody
Anti-Cytokeratin-8 antibody
Anti-Ck-8 antibody
Anti-Keratin-8 antibody
Anti-K8 antibody
Anti-Type-Ii Keratin Kb8 antibody
Anti-KRT8 antibody
Anti-CYK8 antibody

Information sourced from Uniprot.org

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