| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Lysine-specific demethylase 5D demethylase 5D is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KDM5D |
| Gene ID: |
8284 |
| Uniprot ID: |
KDM5D_HUMAN |
| Specificity: |
KDM5D Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein |
| Function | Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. Involved in transcriptional repression of diverse metastasis-associated genes.in this function seems to cooperate with ZMYND8. Suppresses prostate cancer cell invasion. Regulates androgen receptor (AR) transcriptional activity by demethylating H3K4me3 active transcription marks. |
| Protein Name | Lysine-Specific Demethylase 5dHistocompatibility Y AntigenH-YHistone Demethylase Jarid1dJumonji/Arid Domain-Containing Protein 1dProtein SmcyHistone H3-Trimethyl-L-Lysine(4 Demethylase 5d |
| Database Links | Reactome: R-HSA-3214842 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Lysine-Specific Demethylase 5d antibodyAnti-Histocompatibility Y Antigen antibodyAnti-H-Y antibodyAnti-Histone Demethylase Jarid1d antibodyAnti-Jumonji/Arid Domain-Containing Protein 1d antibodyAnti-Protein Smcy antibodyAnti-Histone H3-Trimethyl-L-Lysine(4 Demethylase 5d antibodyAnti-KDM5D antibodyAnti-HY antibodyAnti-HYA antibodyAnti-JARID1D antibodyAnti-KIAA0234 antibodyAnti-SMCY antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
