Western blot analysis of extracts of various cell lines, using KDM4C antibody (STJ110783) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min.

Anti-KDM4C antibody (640-830) (STJ110783)

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STJ110783
£112.50 - £524.50
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KDM4C
Gene ID: 23081
Uniprot ID: KDM4C_HUMAN
Immunogen Region: 640-830
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 640-830 of human KDM4C (NP_055876.2).
Immunogen Sequence: RMKPHCAICTLLMPYHKPDS SNEENDARWETKLDEVVTSE GKTKPLIPEMCFIYSEENIE YSPPNAFLEEDGTSLLISCA KCCVRVHASCYGIPSHEICD GWLCARCKRNAWTAECCLCN LRGGALKQTKNNKWAHVMCA VAVPEVRFTNVPERTQIDVG RIPLQRLKLKCIFCRHRVKR VSGACIQCSYG
Tissue Specificity Overexpressed in several esophageal squamous cell carcinomas (ESCs).
Function Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
Protein Name Lysine-Specific Demethylase 4c
Gene Amplified In Squamous Cell Carcinoma 1 Protein
Gasc-1 Protein
Jmjc Domain-Containing Histone Demethylation Protein 3c
Jumonji Domain-Containing Protein 2c
Histone H3-Trimethyl-L-Lysine(9 Demethylase 4c
Database Links Reactome: R-HSA-3214842
Reactome: R-HSA-5625886
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Lysine-Specific Demethylase 4c antibody
Anti-Gene Amplified In Squamous Cell Carcinoma 1 Protein antibody
Anti-Gasc-1 Protein antibody
Anti-Jmjc Domain-Containing Histone Demethylation Protein 3c antibody
Anti-Jumonji Domain-Containing Protein 2c antibody
Anti-Histone H3-Trimethyl-L-Lysine(9 Demethylase 4c antibody
Anti-KDM4C antibody
Anti-GASC1 antibody
Anti-JHDM3C antibody
Anti-JMJD2C antibody
Anti-KIAA0780 antibody

Information sourced from Uniprot.org

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