Function | Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). Represents the primary spermatozoan K(+) current. The channel underlies a pH-triggered membrane hyperpolarization during the process of sperm capacitation, as sperm encounter the alkaline environment near the ovum in the female reproductive tract, thereby playing an essential for male fertility. |
Protein Name | Potassium Channel Subfamily U Member 1Calcium-Activated Potassium Channel Subunit Alpha-3Calcium-Activated Potassium Channel - Subfamily M Subunit Alpha-3Pore-Forming Subunit Of The Sperm-Specific Alkalization Activated K(+ CurrentKsperSlowpoke Homolog 3Mslo3Ph-Sensitive Maxi Potassium Channel |
Database Links | Reactome: R-MMU-1300642 |
Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinIsoform 2: Cytoplasm |
Alternative Antibody Names | Anti-Potassium Channel Subfamily U Member 1 antibodyAnti-Calcium-Activated Potassium Channel Subunit Alpha-3 antibodyAnti-Calcium-Activated Potassium Channel - Subfamily M Subunit Alpha-3 antibodyAnti-Pore-Forming Subunit Of The Sperm-Specific Alkalization Activated K(+ Current antibodyAnti-Ksper antibodyAnti-Slowpoke Homolog 3 antibodyAnti-Mslo3 antibodyAnti-Ph-Sensitive Maxi Potassium Channel antibodyAnti-Kcnu1 antibodyAnti-Kcnma3 antibodyAnti-Ksper antibodyAnti-Slo3 antibody |
Information sourced from Uniprot.org