Anti-KCNS2 antibody (N-Term) (STJ13101666)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from n-terminal region of mouse KCNS2 (Kv9.2) conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-KCNS2 (N-Term) for use in IHC and WB in Mouse, Rat and Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat/Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1:200 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Kcns2 |
| Gene ID | 16539 |
| Uniprot ID | KCNS2_MOUSE |
| Immunogen | A synthetic peptide from n-terminal region of mouse KCNS2 (Kv9.2) conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | N-Term |
| Specificity | Specific for KCNS2. |
Additional Info
| Function | Potassium channel regulatory subunit that modulate the delayed rectifier voltage-gated potassium channel activity of KCNB1 and KCNB2 by altering their kinetics, expression levels, and shifting the half-inactivation potential to more polarized values. While it does not form functional channels on its own, it can form functional heterotetrameric channels with KCNB1 and KCNB2. Each regulatory subunit has unique regulatory properties that can lead to extensive inhibition, significant changes in kinetics, and/or substantial shifts in the voltage dependencies of the inactivation process. |
| Protein Name | Delayed-Rectifier Potassium Channel Regulatory Subunit Kcns2Delayed-Rectifier K(+ Channel Alpha Subunit 2Delayed-Rectifier Potassium Channel Subunit Kv9.2Potassium Voltage-Gated Channel Subfamily S Member 2 |
| Database Links | Reactome: R-MMU-1296072 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinMay Not Reach The Plasma Membrane But Remain In An Intracellular Compartment In The Absence Of Kcnb1 Or Kcnb2 |
| Alternative Antibody Names | Anti-Delayed-Rectifier Potassium Channel Regulatory Subunit Kcns2 antibodyAnti-Delayed-Rectifier K(+ Channel Alpha Subunit 2 antibodyAnti-Delayed-Rectifier Potassium Channel Subunit Kv9.2 antibodyAnti-Potassium Voltage-Gated Channel Subfamily S Member 2 antibodyAnti-Kcns2 antibody |
Information sourced from Uniprot.org