Western Blot analysis of HEK293 lysis, using primary antibody at 1:1000 dilution. Secondary antibody (STJS000791) was diluted at 1:10000

Anti-KCNS1 antibody (470-550 aa) (STJ191191)

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STJ191191
£48.00 - £252.00
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Potassium voltage-gated channel subfamily S member 1 channel alpha subunit 1 (470-550 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KCNS1
Gene ID: 3787
Uniprot ID: KCNS1_HUMAN
Immunogen Region: 470-550 aa
Specificity: KCNS1 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 470-550
Function Potassium channel regulatory subunit that modulate the delayed rectifier voltage-gated potassium channel activity of KCNB1 and KCNB2 by altering their kinetics, expression levels, and shifting the half-inactivation potential to more polarized values. While it does not form functional channels on its own, it can form functional heterotetrameric channels with KCNB1 and KCNB2. Each regulatory subunit has unique regulatory properties that can lead to extensive inhibition, significant changes in kinetics, and/or substantial shifts in the voltage dependencies of the inactivation process.
Protein Name Delayed-Rectifier Potassium Channel Regulatory Subunit Kcns1
Delayed-Rectifier K(+ Channel Alpha Subunit 1
Delayed-Rectifier Potassium Channel Subunit Kv9.1
Hkv9.1
Potassium Voltage-Gated Channel Modifier Subfamily S Member 1
Database Links Reactome: R-HSA-1296072
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
May Not Reach The Plasma Membrane But Remain In An Intracellular Compartment In The Absence Of Kcnb1 Or Kcnb2
Alternative Antibody Names Anti-Delayed-Rectifier Potassium Channel Regulatory Subunit Kcns1 antibody
Anti-Delayed-Rectifier K(+ Channel Alpha Subunit 1 antibody
Anti-Delayed-Rectifier Potassium Channel Subunit Kv9.1 antibody
Anti-Hkv9.1 antibody
Anti-Potassium Voltage-Gated Channel Modifier Subfamily S Member 1 antibody
Anti-KCNS1 antibody

Information sourced from Uniprot.org

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