| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human/Mouse/Rat/Dog/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-KCNN2 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.3-1µg/mlIHC-3.75µg/mlELISA-antibody detection limit dilution 1:64000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
KCNN2 |
| Gene ID: |
3781 |
| Uniprot ID: |
KCNN2_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_067627.2; NP_740721.1 |
| Specificity: |
This antibody is expected to recognize both isoforms (NP_067627.2; NP_740721.1). |
| Immunogen Sequence: |
ESYDKHVTYNAER |
| Function | Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. |
| Protein Name | Small Conductance Calcium-Activated Potassium Channel Protein 2Sk2Skca 2Skca2Kca2.2 |
| Database Links | Reactome: R-HSA-1296052Reactome: R-HSA-9667769 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Small Conductance Calcium-Activated Potassium Channel Protein 2 antibodyAnti-Sk2 antibodyAnti-Skca 2 antibodyAnti-Skca2 antibodyAnti-Kca2.2 antibodyAnti-KCNN2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
