| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KCNJ5 (50-150) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KCNJ5 |
| Gene ID: |
3762 |
| Uniprot ID: |
KCNJ5_HUMAN |
| Immunogen Region: |
50-150 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human KCNJ5 (NP_000881.3). |
| Immunogen Sequence: |
RQRYMEKSGKCNVHHGNVQE TYRYLSDLFTTLVDLKWRFN LLVFTMVYTVTWLFFGFIWW LIAYIRGDLDHVGDQEWIPC VENLSGFVSAFLFSIETETT I |
| Tissue Specificity | Islets, exocrine pancreas and heart. Expressed in the adrenal cortex, particularly the zona glomerulosa. |
| Function | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium. |
| Protein Name | G Protein-Activated Inward Rectifier Potassium Channel 4Girk-4Cardiac Inward RectifierCirHeart Katp ChannelInward Rectifier K(+ Channel Kir3.4Irk-4Katp-1Potassium Channel - Inwardly Rectifying Subfamily J Member 5 |
| Database Links | Reactome: R-HSA-1296041Reactome: R-HSA-997272 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-G Protein-Activated Inward Rectifier Potassium Channel 4 antibodyAnti-Girk-4 antibodyAnti-Cardiac Inward Rectifier antibodyAnti-Cir antibodyAnti-Heart Katp Channel antibodyAnti-Inward Rectifier K(+ Channel Kir3.4 antibodyAnti-Irk-4 antibodyAnti-Katp-1 antibodyAnti-Potassium Channel - Inwardly Rectifying Subfamily J Member 5 antibodyAnti-KCNJ5 antibodyAnti-GIRK4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
