Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Kv channel-interacting protein 2 is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
KCNIP2 |
Gene ID: |
30819 |
Uniprot ID: |
KCIP2_HUMAN |
Specificity: |
This antibody detects endogenous levels of KCNIP2 at Human, Mouse, Rat |
Immunogen: |
Synthesized peptide derived from human KCNIP2 |
Post Translational Modifications | Palmitoylated. Palmitoylation enhances association with the plasma membrane. |
Function | Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart. |
Protein Name | Kv Channel-Interacting Protein 2Kchip2A-Type Potassium Channel Modulatory Protein 2Cardiac Voltage-Gated Potassium Channel Modulatory SubunitPotassium Channel-Interacting Protein 2 |
Database Links | Reactome: R-HSA-5576894 |
Cellular Localisation | Isoform 1: Cell MembraneLipid-AnchorDetected On Lipid RaftsIsoform 2: Cell MembraneIsoform 6: Cell Membrane |
Alternative Antibody Names | Anti-Kv Channel-Interacting Protein 2 antibodyAnti-Kchip2 antibodyAnti-A-Type Potassium Channel Modulatory Protein 2 antibodyAnti-Cardiac Voltage-Gated Potassium Channel Modulatory Subunit antibodyAnti-Potassium Channel-Interacting Protein 2 antibodyAnti-KCNIP2 antibodyAnti-KCHIP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance