| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KCNIP2 (N-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
KCNIP2 |
| Gene ID: |
30819 |
| Uniprot ID: |
KCIP2_HUMAN |
| Immunogen Region: |
N-Term |
| Specificity: |
Specific for KCNIP2. |
| Immunogen: |
A synthetic peptide from n-terminal region of mouse KCNIP2 (Potassium channel-interacting protein 2) conjugated to an immunogenic carrier protein was used as the antigen. |
| Post Translational Modifications | Palmitoylated. Palmitoylation enhances association with the plasma membrane. |
| Function | Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart. |
| Protein Name | A-Type Potassium Channel Modulatory Protein Kcnip2Cardiac Voltage-Gated Potassium Channel Modulatory SubunitKv Channel-Interacting Protein 2Kchip2Potassium Channel-Interacting Protein 2 |
| Database Links | Reactome: R-HSA-5576894 |
| Cellular Localisation | Isoform 1: Cell MembraneLipid-AnchorDetected On Lipid RaftsIsoform 2: Cell MembraneIsoform 6: Cell Membrane |
| Alternative Antibody Names | Anti-A-Type Potassium Channel Modulatory Protein Kcnip2 antibodyAnti-Cardiac Voltage-Gated Potassium Channel Modulatory Subunit antibodyAnti-Kv Channel-Interacting Protein 2 antibodyAnti-Kchip2 antibodyAnti-Potassium Channel-Interacting Protein 2 antibodyAnti-KCNIP2 antibodyAnti-KCHIP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
