• Western blot analysis of 1) Rat Brain Tissue-Low Molecular Protein Marker, 2) Rat Brain Tissue-High Molecular Protein Marker, 3) Mouse Brain Tissue-Low Molecular Protein Marker, 4) Mouse Brain Tissue- High Molecular Protein Marker, 5) HepG2-Low Molecular P
  • Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using Kv10. 2 Rabbit pAb diluted at 1:200.
  • Immunohistochemical analysis of paraffin-embedded mouse BrainTissue using Kv10. 2 Rabbit pAb diluted at 1:200.

Anti-KCNH5 antibody (264-314 aa) (STJ197359)

SKU:
STJ197359

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Potassium voltage-gated channel subfamily H member 5 (264-314 aa) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
IHC 1:100-200
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KCNH5
Gene ID: 27133
Uniprot ID: KCNH5_HUMAN
Immunogen Region: 264-314 aa
Specificity: Kv10.2 protein (A260) detects endogenous levels of Kv10.2
Immunogen: Synthetic peptide derived from Kv10.2 at the amino acid range 264-314
Function Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel that mediates outward-rectifying potassium currents which, on depolarization, reaches a steady-state level and do not inactivate. The kinetic is characterized by a slow activation time course and a small voltage dependence of the activation time constants, therefore, starts to open at more negative voltages. The activation kinetics depend on the prepulse potential and external divalent cation concentration. The time course of activation is biphasic with a fast and a slowly activating current component. With negative prepulses, the current activation is delayed and slowed down several fold, whereas more positive prepulses speed up activation, therefore the activation rate depends on holding potential.
Protein Name Voltage-Gated Delayed Rectifier Potassium Channel Kcnh5
Ether-A-Go-Go Potassium Channel 2
Heag2
Potassium Voltage-Gated Channel Subfamily H Member 5
Voltage-Gated Potassium Channel Subunit Kv10.2
Database Links Reactome: R-HSA-1296072
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Voltage-Gated Delayed Rectifier Potassium Channel Kcnh5 antibody
Anti-Ether-A-Go-Go Potassium Channel 2 antibody
Anti-Heag2 antibody
Anti-Potassium Voltage-Gated Channel Subfamily H Member 5 antibody
Anti-Voltage-Gated Potassium Channel Subunit Kv10.2 antibody
Anti-KCNH5 antibody
Anti-EAG2 antibody

Information sourced from Uniprot.org

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