| Post Translational Modifications | N-glycosylated. N-glycosylation mediates traffick to the cell membrane but is not necessary for voltage-gated potassium channel activity. |
| Function | Pore-forming (alpha) subunit of a voltage-gated inwardly rectifying potassium channel. Charactherized by a fast rate of activation during depolarization followed by a rapid inactivation at much more depolarized value causing inward rectification due to a C-type inactivation mechanism. Exhibits a rapid recovery from inactivation. |
| Protein Name | Voltage-Gated Inwardly Rectifying Potassium Channel Kcnh3Brain-Specific Eag-Like Channel 1Bec1Ether-A-Go-Go-Like Potassium Channel 2Elk Channel 2Elk2Potassium Voltage-Gated Channel Subfamily H Member 3Voltage-Gated Potassium Channel Subunit Kv12.2 |
| Database Links | Reactome: R-HSA-1296072 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinExpression On The Cell Membrane Requires At Least One Of The Three Glycosylation Sites To Carry A Sugar Chain Irrespective Of Their Positions |
| Alternative Antibody Names | Anti-Voltage-Gated Inwardly Rectifying Potassium Channel Kcnh3 antibodyAnti-Brain-Specific Eag-Like Channel 1 antibodyAnti-Bec1 antibodyAnti-Ether-A-Go-Go-Like Potassium Channel 2 antibodyAnti-Elk Channel 2 antibodyAnti-Elk2 antibodyAnti-Potassium Voltage-Gated Channel Subfamily H Member 3 antibodyAnti-Voltage-Gated Potassium Channel Subunit Kv12.2 antibodyAnti-KCNH3 antibodyAnti-KIAA1282 antibody |
Information sourced from Uniprot.org
