| Host: |
Rabbit |
| Applications: |
IHC/IF |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Potassium voltage-gated channel subfamily G member 3 (335-385 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC 1:100-200IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KCNG3 |
| Gene ID: |
170850 |
| Uniprot ID: |
KCNG3_HUMAN |
| Immunogen Region: |
335-385 aa |
| Specificity: |
Kv10.1 protein (A259) detects endogenous levels of Kv10.1 |
| Immunogen: |
Synthetic peptide derived from Kv10.1 at the amino acid range 335-385 |
| Function | Regulatory subunit of the voltage-gated potassium (Kv) channel which, when coassembled with KCNB1, modulates the kinetics parameters of the heterotetrameric channel namely the inactivation and deactivation rate. Potassium channel subunit that does not form functional channels by itself. Reduces the deactivation rate. Moderately accelerates activation. |
| Protein Name | Voltage-Gated Potassium Channel Regulatory Subunit Kcng3Potassium Voltage-Gated Channel Subfamily G Member 3Voltage-Gated Potassium Channel Subunit Kv10.1Voltage-Gated Potassium Channel Subunit Kv6.3 |
| Database Links | Reactome: R-HSA-1296072 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmHas To Be Associated With Kcnb1 Or Possibly Another Partner To Get Inserted In The Plasma MembraneColocalizes With Kcnb1 At The Plasma MembraneRetains In The Endoplasmic Reticulum In The Absence Of Kcnb1 |
| Alternative Antibody Names | Anti-Voltage-Gated Potassium Channel Regulatory Subunit Kcng3 antibodyAnti-Potassium Voltage-Gated Channel Subfamily G Member 3 antibodyAnti-Voltage-Gated Potassium Channel Subunit Kv10.1 antibodyAnti-Voltage-Gated Potassium Channel Subunit Kv6.3 antibodyAnti-KCNG3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
