Anti-KAZN antibody (65-115 aa) (STJ195836)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human CA196 at the amino acid range 65-115
STJ195836
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General Information

Short DescriptionRabbit polyclonal anti-Kazrin (65-115 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB
HostRabbit
ReactivityHuman/Rat/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

ImmunogenSynthesized peptide derived from the human CA196 at the amino acid range 65-115
Immunogen Region65-115 aa
SpecificityThis antibody detects endogenous levels of CA196 at Human

Additional Info

Function Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known.
Protein Name Kazrin
Database Links Reactome: R-HSA-6809371
Cellular Localisation Cytoplasm
Cytoskeleton
Isoform 2: Cytoplasm
Cell Junction
Desmosome
Nucleus
Observed At The Apical Plasma Membrane Of Keratinocytes
Partially Colocalizes With Ppl And Dp At Desmosomes
And With Pp At The Interdesmosomal Plasma Membrane
Colocalizes With Cortical Actin-Based Membrane Structures
Isoform 3: Cytoplasm
Isoform 4: Cytoplasm
Alternative Antibody Names Anti-Kazrin antibody
Anti-KAZN antibody
Anti-C1orf196 antibody
Anti-KAZ antibody
Anti-KIAA1026 antibody
Anti-HRIHFB2003 antibody

Information sourced from Uniprot.org

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