| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Kazrin (125-175) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KAZN |
| Gene ID: | 23254 |
| Uniprot ID: | KAZRN_HUMAN |
| Immunogen Region: | 125-175 |
| Specificity: | This antibody detects endogenous levels of human KAZRN |
| Immunogen: | Synthesized peptide derived from human KAZRN AA range: 125-175 |
| Function | Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known. |
| Protein Name | Kazrin |
| Database Links | Reactome: R-HSA-6809371 |
| Cellular Localisation | CytoplasmCytoskeletonIsoform 2: CytoplasmCell JunctionDesmosomeNucleusObserved At The Apical Plasma Membrane Of KeratinocytesPartially Colocalizes With Ppl And Dp At DesmosomesAnd With Pp At The Interdesmosomal Plasma MembraneColocalizes With Cortical Actin-Based Membrane StructuresIsoform 3: CytoplasmIsoform 4: Cytoplasm |
| Alternative Antibody Names | Anti-Kazrin antibodyAnti-KAZN antibodyAnti-C1orf196 antibodyAnti-KAZ antibodyAnti-KIAA1026 antibodyAnti-HRIHFB2003 antibody |
Information sourced from Uniprot.org
